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Mutations Enhance the Aggregation Propensity of the Alzheimer’s Aβ Peptide

Aggregation of the amyloid β peptide (Aβ) plays a key role in the molecular etiology of Alzheimer’s disease. Despite the importance of this process, the relationship between the sequence of Aβ and the propensity of the peptide to aggregate has not been fully elucidated. The sequence determinants of...

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Détails bibliographiques
Auteurs principaux: Kim, Woojin, Hecht, Michael H.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346586/
https://ncbi.nlm.nih.gov/pubmed/18258258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.079
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