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Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide
One hundred years ago, Alois Alzheimer observed a relationship between cognitive impairment and the presence of plaque in the brains of patients suffering from the disease that bears his name. The plaque was subsequently shown to be composed primarily of a 42-residue peptide called amyloid β (Aβ) 42...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635087/ https://ncbi.nlm.nih.gov/pubmed/17038501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605629103 |
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