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Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide

One hundred years ago, Alois Alzheimer observed a relationship between cognitive impairment and the presence of plaque in the brains of patients suffering from the disease that bears his name. The plaque was subsequently shown to be composed primarily of a 42-residue peptide called amyloid β (Aβ) 42...

詳細記述

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書誌詳細
主要な著者: Kim, Woojin, Hecht, Michael H.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635087/
https://ncbi.nlm.nih.gov/pubmed/17038501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605629103
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