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Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide

One hundred years ago, Alois Alzheimer observed a relationship between cognitive impairment and the presence of plaque in the brains of patients suffering from the disease that bears his name. The plaque was subsequently shown to be composed primarily of a 42-residue peptide called amyloid β (Aβ) 42...

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Bibliografski detalji
Glavni autori: Kim, Woojin, Hecht, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635087/
https://ncbi.nlm.nih.gov/pubmed/17038501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605629103
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