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Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide

One hundred years ago, Alois Alzheimer observed a relationship between cognitive impairment and the presence of plaque in the brains of patients suffering from the disease that bears his name. The plaque was subsequently shown to be composed primarily of a 42-residue peptide called amyloid β (Aβ) 42...

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Bibliografische gegevens
Hoofdauteurs: Kim, Woojin, Hecht, Michael H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635087/
https://ncbi.nlm.nih.gov/pubmed/17038501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605629103
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