Positive Regulation of Wee1 by Chk1 and 14-3-3 Proteins
Wee1 inactivates the Cdc2–cyclin B complex during interphase by phosphorylating Cdc2 on Tyr-15. The activity of Wee1 is highly regulated during the cell cycle. In frog egg extracts, it has been established previously that Xenopus Wee1 (Xwee1) is present in a hypophosphorylated, active form during in...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Cell Biology
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11251070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.3.551 |
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