Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

The checkpoint kinase Xchk1 becomes phosphorylated in Xenopus egg extracts in response to DNA replication blocks or UV-damaged DNA. Xchk1 is also required for the cell cycle delay that is induced by unreplicated or UV-damaged DNA. In this report, we have removed the Xenopus homolog of ATR (Xatr) fro...

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Bibliografske podrobnosti
Main Authors: Guo, Zijian, Kumagai, Akiko, Wang, Sophie X., Dunphy, William G.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2000
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC317027/
https://ncbi.nlm.nih.gov/pubmed/11069891
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