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Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors.

Proliferating eukaryotic cells possess checkpoint mechanisms that block cell division in the presence of unreplicated or damaged DNA. Using cell-free extracts from Xenopus eggs, we have investigated the mechanisms underlying the inability of a recombinant Cdc2/cyclin B complex to induce mitosis in t...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphov: Kumagai, A, Dunphy, W G
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Cell Biology 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7787246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.2.199
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