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From Sugar to Fat: How the Transcription Factor XBP1 Regulates Hepatic Lipogenesis

Lipogenesis occurs primarily in the liver, where dietary carbohydrates control the expression of key enzymes in glycolytic and lipogenic pathways. We have recently discovered that the transcription factor XBP1, best known as a key regulator of the unfolded protein response (UPR), is required for de...

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Hlavní autoři: Glimcher, Laurie H., Lee, Ann-Hwee
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096021/
https://ncbi.nlm.nih.gov/pubmed/19751410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.04956.x
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