Ablation of Glutaredoxin-1 Attenuates Lipopolysaccharide-Induced Lung Inflammation and Alveolar Macrophage Activation

Protein S-glutathionylation (PSSG), a reversible posttranslational modification of reactive cysteines, recently emerged as a regulatory mechanism that affects diverse cell-signaling cascades. The extent of cellular PSSG is controlled by the oxidoreductase glutaredoxin-1 (Grx1), a cytosolic enzyme th...

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Bibliographische Detailangaben
Hauptverfasser: Aesif, Scott W., Anathy, Vikas, Kuipers, Ine, Guala, Amy S., Reiss, Jessica N., Ho, Ye-Shih, Janssen-Heininger, Yvonne M. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095922/
https://ncbi.nlm.nih.gov/pubmed/20539014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0136OC
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