Activation of the glutaredoxin-1 gene by Nuclear Factor kappa B enhances signaling

The transcription factor, Nuclear Factor kappa B (NF-κB) is a critical regulator of inflammation and immunity, and is negatively regulated via S-glutathionylation. The inhibitory effect of S-glutathionylation is overcome by glutaredoxin-1 (Grx1), which under physiological conditions catalyses deglut...

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Bibliografiska uppgifter
Huvudupphovsmän: Aesif, Scott W., Kuipers, Ine, van der Velden, Jos, Tully, Jane E., Guala, Amy S., Anathy, Vikas, Sheely, Juliana I., Reynaert, Niki L., Wouters, Emiel F. M., van der Vliet, Albert, Janssen-Heininger, Yvonne M. W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181077/
https://ncbi.nlm.nih.gov/pubmed/21762778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.06.025
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