The glutaredoxin/S-glutathionylation axis regulates interleukin 17A-induced pro-inflammatory responses in lung epithelial cells in association with S-glutathionylation of Nuclear Factor kappa B family proteins

Interleukin-17A (IL-17A) is a newly emerging player in the pathogenesis of chronic lung diseases that amplifies inflammatory responses and promotes tissue remodeling. Stimulation of lung epithelial cells with IL-17A leads to activation of the transcription factor, nuclear factor kappa B (NF-κB), a k...

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Main Authors: Nolin, James D., Tully, Jane E., Hoffman, Sidra M., Guala, Amy S., van der Velden, Jos L., Poynter, Matthew E., van der Vliet, Albert, Anathy, Vikas, Janssen-Heininger, Yvonne M.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111997/
https://ncbi.nlm.nih.gov/pubmed/24816292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.04.028
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