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Synaptotagmin Perturbs the Structure of Phospholipid Bilayers

Synaptotagmin I (syt), an integral protein of the synaptic vesicle membrane, is believed to act as a Ca(2+) sensor for neuronal exocytosis. Syt’s cytoplasmic domain consists largely of two C2 domains, C2A and C2B. In response to Ca(2+) binding, the C2 domains interact with membranes, becoming partia...

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Detalhes bibliográficos
Main Authors: Shahin, Victor, Datta, Debajyoti, Hui, Enfu, Henderson, Robert M., Chapman, Edwin R., Edwardson, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095487/
https://ncbi.nlm.nih.gov/pubmed/18205405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701879g
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