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Amyloid β-Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide

Generation of reactive oxygen species (ROS) causes cellular oxidative damage and has been implicated in the etiology of Alzheimer's disease (AD). In contrast, multiple lines of evidence indicate that ROS can normally modulate long-term potentiation (LTP), a cellular model for memory formation....

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Detalhes bibliográficos
Main Authors: Ma, Tao, Hoeffer, Charles A., Wong, Helen, Massaad, Cynthia A., Zhou, Ping, Iadecola, Costantino, Murphy, Michael P., Pautler, Robia G., Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095121/
https://ncbi.nlm.nih.gov/pubmed/21490199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6566-10.2011
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