AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity

AKT is a kinase regulating numerous cellular processes in the brain, and mutations in AKT are known to affect brain function. AKT is indirectly implicated in synaptic plasticity, but its direct role has not been studied. Moreover, three highly related AKT isoforms are expressed in the brain, but the...

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Vydáno v:eLife
Hlavní autoři: Levenga, Josien, Wong, Helen, Milstead, Ryan A, Keller, Bailey N, LaPlante, Lauren E, Hoeffer, Charles A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722612/
https://ncbi.nlm.nih.gov/pubmed/29173281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30640
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