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Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease characterized by impaired cognitive function and the deposition of extracellular amyloid plaques and intracellular tangles. Although the proximal cause of AD is not well understood, it is clear that amyloid-β (Aβ) plays a critical role in...

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Detalhes bibliográficos
Main Authors: Massaad, Cynthia A., Washington, Taneasha M., Pautler, Robia G., Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726352/
https://ncbi.nlm.nih.gov/pubmed/19666610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902714106
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