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Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease
Alzheimer’s disease is caused by increased production or reduced clearance of amyloid-β, which results in the formation amyloid-β plaques and triggers a cascade of downstream events leading to progressive neurodegeneration. The earliest clinical symptoms of Alzheimer’s disease, i.e., memory loss, ar...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149201/ https://ncbi.nlm.nih.gov/pubmed/24974208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0076-z |
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