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Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels

Synaptic plasticity requires remodeling of the actin cytoskeleton. Although two actin isoforms, β- and γ-actin, are expressed in dendritic spines, the specific contribution of γ-actin in the expression of synaptic plasticity is unknown. We show that synaptic γ-actin levels are regulated by the E3 ub...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Schreiber, Joerg, Végh, Marlene J., Dawitz, Julia, Kroon, Tim, Loos, Maarten, Labonté, Dorthe, Li, Ka Wan, Van Nierop, Pim, Van Diepen, Michiel T., De Zeeuw, Chris I., Kneussel, Matthias, Meredith, Rhiannon M., Smit, August B., Van Kesteren, Ronald E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639863/
https://ncbi.nlm.nih.gov/pubmed/26527743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506048
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