Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels

Synaptic plasticity requires remodeling of the actin cytoskeleton. Although two actin isoforms, β- and γ-actin, are expressed in dendritic spines, the specific contribution of γ-actin in the expression of synaptic plasticity is unknown. We show that synaptic γ-actin levels are regulated by the E3 ub...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Schreiber, Joerg, Végh, Marlene J., Dawitz, Julia, Kroon, Tim, Loos, Maarten, Labonté, Dorthe, Li, Ka Wan, Van Nierop, Pim, Van Diepen, Michiel T., De Zeeuw, Chris I., Kneussel, Matthias, Meredith, Rhiannon M., Smit, August B., Van Kesteren, Ronald E.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
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Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639863/
https://ncbi.nlm.nih.gov/pubmed/26527743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506048
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