Amyloid β-Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide

Generation of reactive oxygen species (ROS) causes cellular oxidative damage and has been implicated in the etiology of Alzheimer's disease (AD). In contrast, multiple lines of evidence indicate that ROS can normally modulate long-term potentiation (LTP), a cellular model for memory formation....

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Autores principales: Ma, Tao, Hoeffer, Charles A., Wong, Helen, Massaad, Cynthia A., Zhou, Ping, Iadecola, Costantino, Murphy, Michael P., Pautler, Robia G., Klann, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095121/
https://ncbi.nlm.nih.gov/pubmed/21490199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6566-10.2011
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