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Vaccination Alters the Balance between Protective Immunity, Exhaustion, Escape, and Death in Chronic Infections
While T cell-based vaccines have the potential to provide protection against chronic virus infections, they also have the potential to generate immunopathology following subsequent virus infection. We develop a mathematical model to investigate the conditions under which T cells lead to protection v...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094965/ https://ncbi.nlm.nih.gov/pubmed/21411537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00166-11 |
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