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Estimation of the rate of killing by cytotoxic T lymphocytes in vivo

Cytotoxic T lymphocytes (CTL) help control virus infections by killing virus-infected (target) cells. How fast do CTL find and kill target cells in vivo? Experiments allow us to follow populations of labeled target cells after their transfer into immune mice where they are killed by CTL. Here, we de...

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Autors principals: Regoes, Roland R., Barber, Daniel L., Ahmed, Rafi, Antia, Rustom
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785271/
https://ncbi.nlm.nih.gov/pubmed/17242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508830104
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