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Estimation of the rate of killing by cytotoxic T lymphocytes in vivo

Cytotoxic T lymphocytes (CTL) help control virus infections by killing virus-infected (target) cells. How fast do CTL find and kill target cells in vivo? Experiments allow us to follow populations of labeled target cells after their transfer into immune mice where they are killed by CTL. Here, we de...

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Detalhes bibliográficos
Main Authors: Regoes, Roland R., Barber, Daniel L., Ahmed, Rafi, Antia, Rustom
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785271/
https://ncbi.nlm.nih.gov/pubmed/17242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508830104
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