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Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities

Cytotoxic T lymphocytes (CTLs) are important agents in the control of intracellular pathogens, which specifically recognize and kill infected cells. Recently developed experimental methods allow the estimation of the CTL's efficacy in detecting and clearing infected host cells. One method, the...

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Publicado en:PLoS Comput Biol
Autores principales: Garcia, Victor, Richter, Kirsten, Graw, Frederik, Oxenius, Annette, Regoes, Roland R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416789/
https://ncbi.nlm.nih.gov/pubmed/25933039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004178
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