Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities

Cytotoxic T lymphocytes (CTLs) are important agents in the control of intracellular pathogens, which specifically recognize and kill infected cells. Recently developed experimental methods allow the estimation of the CTL's efficacy in detecting and clearing infected host cells. One method, the...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Garcia, Victor, Richter, Kirsten, Graw, Frederik, Oxenius, Annette, Regoes, Roland R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416789/
https://ncbi.nlm.nih.gov/pubmed/25933039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004178
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