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Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities

Cytotoxic T lymphocytes (CTLs) are important agents in the control of intracellular pathogens, which specifically recognize and kill infected cells. Recently developed experimental methods allow the estimation of the CTL's efficacy in detecting and clearing infected host cells. One method, the...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Garcia, Victor, Richter, Kirsten, Graw, Frederik, Oxenius, Annette, Regoes, Roland R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416789/
https://ncbi.nlm.nih.gov/pubmed/25933039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004178
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