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Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection

Immune responses mediated by cytotoxic T lymphocytes (CTLs) have often been found to be functionally impaired in persistent infections. It is assumed that this impairment contributes to persistence of the infection. In this study, we compare the killing efficacy of CD8(+) T-cell responses in mice ac...

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Autors principals: Graw, Frederik, Richter, Kirsten, Oxenius, Annette, Regoes, Roland R.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177638/
https://ncbi.nlm.nih.gov/pubmed/21450739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.0453
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