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Revisiting Estimates of CTL Killing Rates In Vivo

Recent experimental advances have allowed the estimation of the in vivo rates of killing of infected target cells by cytotoxic T lymphocytes (CTL). We present several refinements to a method applied previously to quantify killing of targets in the spleen using a dynamical model. We reanalyse data pr...

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Autors principals: Yates, Andrew, Graw, Frederik, Barber, Daniel L., Ahmed, Rafi, Regoes, Roland R., Antia, Rustom
Format: Artigo
Idioma:Inglês
Publicat: Public Libidenry of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111049/
https://ncbi.nlm.nih.gov/pubmed/18074025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001301
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