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Estimation of the rate of killing by cytotoxic T lymphocytes in vivo

Cytotoxic T lymphocytes (CTL) help control virus infections by killing virus-infected (target) cells. How fast do CTL find and kill target cells in vivo? Experiments allow us to follow populations of labeled target cells after their transfer into immune mice where they are killed by CTL. Here, we de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Regoes, Roland R., Barber, Daniel L., Ahmed, Rafi, Antia, Rustom
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785271/
https://ncbi.nlm.nih.gov/pubmed/17242364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508830104
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