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Inefficient Cytotoxic T Lymphocyte–Mediated Killing of HIV-1–Infected Cells In Vivo

Understanding the role of cytotoxic T lymphocytes (CTLs) in controlling HIV-1 infection is vital for vaccine design. However, it is difficult to assess the importance of CTLs in natural infection. Different human leukocyte antigen (HLA) class I alleles are associated with different rates of progress...

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Detalhes bibliográficos
Main Authors: Asquith, Becca, Edwards, Charles T. T, Lipsitch, Marc, McLean, Angela R
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395353/
https://ncbi.nlm.nih.gov/pubmed/16515366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040090
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