The Naturally Attenuated Kunjin Strain of West Nile Virus Shows Enhanced Sensitivity to the Host Type I Interferon Response

The host determinants that contribute to attenuation of the naturally occurring nonpathogenic strain of West Nile virus (WNV), the Kunjin strain (WNV(KUN)), remain unknown. Here, we show that compared to a highly pathogenic North American strain, WNV(KUN) exhibited an enhanced sensitivity to the ant...

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Autors principals: Daffis, Stephane, Lazear, Helen M., Liu, Wen Jun, Audsley, Michelle, Engle, Michael, Khromykh, Alexander A., Diamond, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094947/
https://ncbi.nlm.nih.gov/pubmed/21411525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-11
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