Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection

Protection against West Nile virus (WNV) infection requires rapid viral sensing and the generation of an interferon (IFN) response. Mice lacking IFN regulatory factor 3 (IRF-3) show increased vulnerability to WNV infection with enhanced viral replication and blunted IFN-stimulated gene (ISG) respons...

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Detalhes bibliográficos
Main Authors: Daffis, Stephane, Samuel, Melanie A., Suthar, Mehul S., Gale, Michael, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573187/
https://ncbi.nlm.nih.gov/pubmed/18715906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00935-08
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