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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection

Protection against West Nile virus (WNV) infection requires rapid viral sensing and the generation of an interferon (IFN) response. Mice lacking IFN regulatory factor 3 (IRF-3) show increased vulnerability to WNV infection with enhanced viral replication and blunted IFN-stimulated gene (ISG) respons...

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Autors principals: Daffis, Stephane, Samuel, Melanie A., Suthar, Mehul S., Gale, Michael, Diamond, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573187/
https://ncbi.nlm.nih.gov/pubmed/18715906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00935-08
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