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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection
Protection against West Nile virus (WNV) infection requires rapid viral sensing and the generation of an interferon (IFN) response. Mice lacking IFN regulatory factor 3 (IRF-3) show increased vulnerability to WNV infection with enhanced viral replication and blunted IFN-stimulated gene (ISG) respons...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573187/ https://ncbi.nlm.nih.gov/pubmed/18715906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00935-08 |
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