Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8(+) T Cell Immune Responses against West Nile Virus Infection

Interferon regulatory factor (IRF)-1 is an immunomodulatory transcription factor that functions downstream of pathogen recognition receptor signaling and has been implicated as a regulator of type I interferon (IFN)-αβ expression and the immune response to virus infections. However, this role for IR...

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Detalhes bibliográficos
Principais autores: Brien, James D., Daffis, Stephane, Lazear, Helen M., Cho, Hyelim, Suthar, Mehul S., Gale, Michael, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164650/
https://ncbi.nlm.nih.gov/pubmed/21909274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002230
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