The Naturally Attenuated Kunjin Strain of West Nile Virus Shows Enhanced Sensitivity to the Host Type I Interferon Response

The host determinants that contribute to attenuation of the naturally occurring nonpathogenic strain of West Nile virus (WNV), the Kunjin strain (WNV(KUN)), remain unknown. Here, we show that compared to a highly pathogenic North American strain, WNV(KUN) exhibited an enhanced sensitivity to the ant...

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Detalhes bibliográficos
Main Authors: Daffis, Stephane, Lazear, Helen M., Liu, Wen Jun, Audsley, Michelle, Engle, Michael, Khromykh, Alexander A., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094947/
https://ncbi.nlm.nih.gov/pubmed/21411525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-11
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