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Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency

PEGylated cationic polymers have been extensively studied for substituting virus as gene delivery vehicles. These polymers can produce water-soluble polyionic complexes (polyplexes) with plasmid DNA (pDNA) and show enhanced stability compared to non-PEGylated polyplexes. However, PEGylation always d...

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Sonraí Bibleagrafaíochta
Main Authors: Lai, Tsz Chung, Kataoka, Kazunori, Kwon, Glen S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094566/
https://ncbi.nlm.nih.gov/pubmed/21453964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.02.065
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