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pH-Sensitive Multi-PEGylated Block Copolymer as a Bioresponsive pDNA Delivery Vector

PURPOSE: A reversibly-PEGylated diblock copolymer, poly(aspartate-hydrazide-poly(ethylene glycol))-block-poly(aspartate-diaminoethane) (p[Asp(Hyd-PEG)]-b-p[Asp(DET)]) was reported here for enhanced gene transfection and colloidal stability. The diblock copolymer possessed a unique architecture based...

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Detalhes bibliográficos
Main Authors: Lai, Tsz Chung, Bae, Younsoo, Yoshida, Takayuki, Kataoka, Kazunori, Kwon, Glen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917510/
https://ncbi.nlm.nih.gov/pubmed/20300803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0092-z
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