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Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel
Poly(ethylene glycol)-block-poly(aspartate-hydrazide) (PEG-p(Asp-Hyd)) was modified using either levulinic acid (LEV) or 4-acetyl benzoic acid (4AB) attached via hydrazone bonds. Paclitaxel (PTX) conjugated to the linkers formed PEG-p(Asp-Hyd-LEV-PTX) and PEG-p(Asp-Hyd-4AB-PTX). PEG-p(Asp-Hyd-LEV-PT...
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| Publicado en: | Biomaterials |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428330/ https://ncbi.nlm.nih.gov/pubmed/19959225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.11.038 |
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