Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel

Poly(ethylene glycol)-block-poly(aspartate-hydrazide) (PEG-p(Asp-Hyd)) was modified using either levulinic acid (LEV) or 4-acetyl benzoic acid (4AB) attached via hydrazone bonds. Paclitaxel (PTX) conjugated to the linkers formed PEG-p(Asp-Hyd-LEV-PTX) and PEG-p(Asp-Hyd-4AB-PTX). PEG-p(Asp-Hyd-LEV-PT...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomaterials
Prif Awduron: Alani, Adam WG., Bae, Younsoo, Rao, Deepa A., Kwon, Glen S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428330/
https://ncbi.nlm.nih.gov/pubmed/19959225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.11.038
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