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Physicochemical stability and transfection efficiency of cationic amphiphilic copolymer/pDNA polyplexes for spinal cord injury repair

Multiple age-related and injury-induced characteristics of the adult central nervous system (CNS) pose barriers to axonal regeneration and functional recovery following injury. In situ gene therapy is a promising approach to address the limited availability of growth-promoting biomolecules at CNS in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gwak, So-Jung, Macks, Christian, Bae, Sooneon, Cecil, Noah, Lee, Jeoung Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595900/
https://ncbi.nlm.nih.gov/pubmed/28900263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10982-y
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