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RhoA knockdown by cationic amphiphilic copolymer/siRhoA polyplexes enhances axonal regeneration in rat spinal cord injury model

Spinal cord injury (SCI) results in permanent loss of motor and sensory function due to developmentally-related and injured-induced changes in the extrinsic microenvironment and intrinsic neuronal biochemistry that limit plasticity and axonal regeneration. Our long term goal is to develop cationic,...

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Dettagli Bibliografici
Pubblicato in:Biomaterials
Autori principali: Gwak, So-Jung, Macks, Christian, Jeong, Da Un, Kindy, Mark, Lynn, Michael, Webb, Ken, Lee, Jeoung Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315572/
https://ncbi.nlm.nih.gov/pubmed/28088077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.01.003
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