MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

Although it is well established that tumors initiate an angiogenic switch, the molecular basis of this process remains incompletely understood. Here we show that the miRNA miR-132 acts as an angiogenic switch by targeting p120RasGAP in the endothelium and thereby inducing neovascularization. We iden...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Anand, Sudarshan, Majeti, Bharat K, Acevedo, Lisette M, Murphy, Eric A, Mukthavaram, Rajesh, Scheppke, Lea, Huang, Miller, Shields, David J, Lindquist, Jeffrey N, Lapinski, Philip E, King, Philip D, Weis, Sara M, Cheresh, David A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094020/
https://ncbi.nlm.nih.gov/pubmed/20676106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2186
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller