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A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells

Directional motility is a complex process requiring the spatiotemporal integration of signals that regulate cytoskeletal changes, and the establishment of an anteroposterior or polarized cell axis. Focal adhesion kinase (FAK) promotes cell migration, but a molecular role for FAK in promoting cell po...

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Detalles Bibliográficos
Main Authors: Tomar, Alok, Lim, Ssang-Taek, Lim, Yangmi, Schlaepfer, David D.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684836/
https://ncbi.nlm.nih.gov/pubmed/19435801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046870
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