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A role for p120 RasGAP (RASA1) in thymocyte positive selection and survival of naïve T cells
Activation of the Ras small GTP-binding protein is necessary for normal T cell development and function. However, which of a number of Ras GTPase activating proteins (RasGAPs) inactivate Ras in T cells is unknown. We used a T cell-specific RASA1-deficient mouse model to investigate the role of the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119767/ https://ncbi.nlm.nih.gov/pubmed/21646295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100178 |
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