The Ras GTPase-activating Protein Neurofibromin 1 Promotes the Positive Selection of Thymocytes

TCR-mediated activation of the Ras signaling pathway is critical for T cell development in the thymus and function in the periphery. However, which members of a family of Ras GTPase-activating proteins (RasGAPs) negatively-regulate Ras activation in T cells is unknown. In this study we examined a po...

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Détails bibliographiques
Auteurs principaux: Oliver, Jennifer A., Lapinski, Philip E., Lubeck, Beth A., Turner, Jackson S., Parada, Luis F., Zhu, Yuan, King, Philip D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646930/
https://ncbi.nlm.nih.gov/pubmed/23522726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.03.005
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