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Site-specific integrase-mediated transgenesis in mice via pronuclear injection

Microinjection of recombinant DNA into zygotic pronuclei has been widely used for producing transgenic mice. However, with this method, the insertion site, integrity, and copy number of the transgene cannot be controlled. Here, we present an integrase-based approach to produce transgenic mice via pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tasic, Bosiljka, Hippenmeyer, Simon, Wang, Charlene, Gamboa, Matthew, Zong, Hui, Chen-Tsai, Yanru, Luo, Liqun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093482/
https://ncbi.nlm.nih.gov/pubmed/21464299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019507108
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