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Site-specific integrase-mediated transgenesis in mice via pronuclear injection
Microinjection of recombinant DNA into zygotic pronuclei has been widely used for producing transgenic mice. However, with this method, the insertion site, integrity, and copy number of the transgene cannot be controlled. Here, we present an integrase-based approach to produce transgenic mice via pr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093482/ https://ncbi.nlm.nih.gov/pubmed/21464299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019507108 |
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