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Structures of human exonuclease I DNA complexes suggest a unified mechanism for nuclease family
Human exonuclease 1 (hExo1) plays important roles in DNA repair and recombination processes that maintain genomic integrity. It is a member of the 5′ structure-specific nuclease family of exonucleases and endonucleases that includes FEN-1, XPG, and GEN1. We present structures of hExo1 in complex wit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093132/ https://ncbi.nlm.nih.gov/pubmed/21496642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.005 |
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