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Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate

Protein geranylgeranyltransferase-I (GGTase-I) catalyzes the transfer of a 20-carbon isoprenoid lipid to the sulfur of a cysteine residue located near the C terminus of numerous cellular proteins, including members of the Rho superfamily of small GTPases and other essential signal transduction prote...

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Detalhes bibliográficos
Main Authors: Hast, Michael A., Beese, Lorena S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581548/
https://ncbi.nlm.nih.gov/pubmed/18713740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805330200
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