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Structure of mammalian protein geranylgeranyltransferase type-I
Protein geranylgeranyltransferase type-I (GGTase-I), one of two CaaX prenyltransferases, is an essential enzyme in eukaryotes. GGTase-I catalyzes C-terminal lipidation of >100 proteins, including many GTP- binding regulatory proteins. We present the first structural information for mammalian GGTa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275430/ https://ncbi.nlm.nih.gov/pubmed/14609943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg571 |
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