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Effects of Pharmacologic Inhibition of Protein Geranylgeranyltransferase Type I on Aqueous Humor Outflow through the Trabecular Meshwork
PURPOSE: To determine the effects of inhibition of protein geranylgeranyltransferase type I (GGTase-I), which isoprenylates so-called CaaX proteins, including the GTP-binding proteins such as Rho GTPases and the βγ subunits of heterotrimeric G-proteins, on aqueous humor outflow and trabecular meshwo...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561264/ https://ncbi.nlm.nih.gov/pubmed/18316706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1639 |
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