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Connective Tissue Growth Factor–Mediated Upregulation of Neuromedin U Expression in Trabecular Meshwork Cells and its Role in Homeostasis of Aqueous Humor Outflow

PURPOSE. Connective tissue growth factor (CTGF) is a matricellular protein presumed to be involved in the pathobiology of various fibrotic diseases, including glaucoma. We investigated the effects of Rho GTPase-dependent actin cytoskeletal integrity on CTGF expression and CTGF-induced changes in gen...

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Bibliografiske detaljer
Main Authors: Iyer, Padma, Maddala, Rupalatha, Pattabiraman, Padmanabhan P., Rao, Ponugoti Vasantha
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410677/
https://ncbi.nlm.nih.gov/pubmed/22761259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9681
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