טוען...
Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I
Human exonuclease 1 (hExo1) is a member of the RAD2/XPG structure-specific 5′-nuclease superfamily. Its dominant, processive 5′–3′ exonuclease and secondary 5′-flap endonuclease activities participate in various DNA repair, recombination, and replication processes. A single active site processes bot...
שמור ב:
הוצא לאור ב: | Proc Natl Acad Sci U S A |
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Main Authors: | , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2017
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468604/ https://ncbi.nlm.nih.gov/pubmed/28533382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704845114 |
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