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Selective Incorporation of Polyanionic Molecules into Hamster Prions
The central pathogenic event of prion disease is the conformational conversion of a host protein, PrP(C), into a pathogenic isoform, PrP(Sc). We previously showed that the protein misfolding cyclic amplification (PMCA) technique can be used to form infectious prion molecules de novo from purified na...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091164/ https://ncbi.nlm.nih.gov/pubmed/17940287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704447200 |
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