FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ

Nimustine (ACNU) and temozolomide (TMZ) are DNA alkylating agents which are commonly used in chemotherapy for glioblastomas. ACNU is a DNA cross-linking agent and TMZ is a methylating agent. The therapeutic efficacy of these agents is limited by the development of resistance. In this work, the role...

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Detaylı Bibliyografya
Asıl Yazarlar: Kondo, Natsuko, Takahashi, Akihisa, Mori, Eiichiro, Noda, Taichi, Zdzienicka, Małgorzata Z., Thompson, Larry H., Helleday, Thomas, Suzuki, Minoru, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji, Hasegawa, Masatoshi, Ohnishi, Takeo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090409/
https://ncbi.nlm.nih.gov/pubmed/21573016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019659
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